WP1 - Spread and transmission of A&ARB&ARG under wastewater reuse scenarios
Lead Beneficiary: UCP (Dr. Celia Manaia)
Duration: 3-45 months
Objectives:
understand the mechanisms related to the fate/evolution of antibiotics and antibiotic-resistant bacteria and antibiotic resistance genes (A&ARB&ARG) transmission from treated wastewater to soil, crops, water resources;
- determine appropriate conditions for controlling their spread;
- assess the risks of ARB&ARG transmission to humans through the consumption of raw vegetables.

WP2 - Evaluation of A&ARB&ARG effects and hazard identification
Lead Beneficiary: KWR (Dr. Luc Hornstra)
Duration: 3-45 months
Objectives:
develop novel tools for the detection of antibiotic resistance (AR) in wastewater, water, soil and crops;
apply innovative batteries of advanced tests for the evaluation of effects of antibiotics, their metabolites and transformation products (TPs) in treated wastewater.

WP3 - Innovative technological solutions for the removal of A&ARB&ARG
Lead Beneficiary: Adventech (Mr. Sergio Silva)
Duration: 4-45 months
Objectives:
evaluate the efficiency of innovative standalone/integrated technologies for minimizing antibiotics and antibiotic-resistant bacteria and antibiotic resistance genes (A&ARB&ARG);
evaluate the effect of innovative disinfection on antibiotic resistance (AR) transfer;
develop and test new materials for ceramic membranes and fixed catalysts;
design new photocatalytic reactor;
determine the market penetration potential of the new technology to be developed.

WP4 - A&ARB&ARG fate prediction through modelling approaches
Lead Beneficiary: TUD (Prof. Thomas Berendonk)
Duration: 3-45 months
Objectives:
develop models to describe/predict the fate of antibiotics and antibiotic-resistant bacteria and antibiotic resistance genes (A&ARB&ARG) from sludge to treated wastewater to soil, ground/surface water, and crops allowing the development of a scientific base for risk assessment in relation to specific environmental parameters for A&ARB&ARG transmission and enrichment;
identify key parameters and processes necessary for mathematical modelling to describe A&ARB&ARG fate in sludge, water, soil, crops;
develop harmonization and equivalence among different modelling approaches and a link to the common databank in WP5.

WP5 - Data management, prioritization and policy guidelines development
Duration: 3-45 months
Objectives:
To integrate all empirical data in a web-based database for:
automated prioritization of chemical/biological risk factors;
use of data in models for large-scale projections;
use of data for policy development;
derivation of science-based emission limits values (ELVs) for antibiotics, transformation products (TPs) and antibiotic-resistant bacteria and antibiotic resistance genes (ARB&ARG) in wastewater.

WP6 - Training
Duration: 4-48 months
Objectives:
fundamental and applied scientific knowledge, hands-on experience on state-of-the-art techniques/technologies/systems;
knowledge on European policies on water/wastewater;
exposure to a variety of research fields and groups, and sectors i.e. academia, private sector, industrial sector, policy makers;
complimentary skills;
experiences with various cultures/countries;
opportunities for the Early-Stage Researchers (ESRs) to convey their research outside the labs at scientific and general public audiences.

WP7 - Management
Duration: 1-48 months
Objectives:
project activities coordination;
development of Consortium Agreement;
progress monitoring and evaluation of individual projects;
quality control and risk management;
financial management;
organization of meetings;
delivery of progress reports/deliverables;
Intellectual Property Rights (IPR) management.

WP8 - Communication and Dissemination
Duration: 1-48 months
Objectives:
dissemination of research results to key stakeholders; policy makers, end-users, wastewater treatment plant operators/managers, scientific community and the general public;
increasing environmental awareness and participation of the general public;
promoting internal and external networking;
publication of research results;
outreach activities;
exploitation of results.
